1H NMR spectra of a series of complexes [PtCl(Eugenol-1H)(amine)] (amine: pyridine, 4-Me-pyridine, quinoline, p-cloaniline, p-toluidine)

The 1H NMR spectra of five complexes of the genenal formula [PtCl(eugenol-1H)(amine)] (amine: pyridine (2), 4-Me-pyridine (3), quinoline (4), p-cloaniline (5), p-toluidine (6)) in d6-acetone and CDCl3 solvents were studied. The result showed that in d1-chloroform, complexes 2÷5 gave two stable over time sets of signals which corresponded with two existence forms of the complexes in the solution: two strong intermolecular interactions (Cl3C-H…ClPt(II) hydrogen bond and Cl2HC-Cl…Pt(II) halogen bond) for 2, 3, 4; and two strong hydrogen bonds (NH2…Cl-Pt(II) intramolecular bond and Cl3C-H…Cl-aniline intermolecular bond) for 5. Meanwhile, in d6-acetone solvent, complexes containing aniline derivatives, 5 and 6, revealed an isomerization, that was, the amine group transfered from cis position to trans position compared with the allyl group of eugenol. This conversion process reached an equilibrium after 48 hours.

Analysis of Superpave mix design for asphalt mixture and some experimental research results

Superpave is one of the outstanding products of the Strategic Highway Research Program (SHRP) in the world. The Superpave mix design procedure involves selecting PG bitumen and aggregate materials to design the asphalt mixture, meeting the requirements on the basis of traffic speed and traffic level, to prevent pavement damage such as fatigue cracking, thermal cracking, permanent deformation (rutting) during operation. This paper analyses the Superpave mix design for asphalt mixture and presents some experimental research results in laboratory in Vietnam.

Expression of genes involving in JAK/STAT signaling pathway and inflammation in patients with lymphoma

Lymphoma is a malignant cancer that originates from the uncontrolled growth of lymphocytes in the immune system. Lymphoma is one of the cancer types with the highest incidence and mortality rate worldwide and in Vietnam. The pathogenesis of lymphoma is characterized by various factors including the JAK/STAT signaling pathway through abnormal activation of STAT genes and the disorders of immune regulation. This study aims to determine the expression of mRNA of genes in relation to JAK/STAT pathway including Klotho, STAT1, STAT3, STAT5, and STAT6 as well as immune regulatory genes LAG-3, CTLA-4, and PD-1 by realtime PCR method to explore their roles in lymphoma. At the same time, the levels of TNF-α in serum samples were also measured by ELISA method. The results showed that the relative expressions of STAT1, STAT3, and STAT5 were significantly higher while LAG-3 expression was lower in patients with lymphoma compared to controls. The TNF-α levels in lymphoma patients were 7.789 pg/ml which was dramatically higher than these of the controls. The results indicated that STAT1, STAT3, STAT5, and LAG-3 might be considered as potential biomarkers for early detection of lymphoma.

 

Effect of variety and cultivation place on the quality of tea (Camellia sinensis O. Kuntze) seed and tea seed oil in Vietnam

The quality of tea seeds and tea seed oils from four popular tea varieties in Vietnam, namely Trungdu, Shan, PH1, and LDP1, grown in Phu Tho, Tuyen Quang, Thai Nguyen, Yen Bai, Nghe An, Quang Tri, and Lao Cai provinces has been identified. The recovery rate of fresh tea seeds ranged from 52.66-64.69%. Chemical components in tea seeds such as protein, ash, lipid and polyphenol content varied in different varieties, but the results of different cultivation places showed no significant difference. In general, the  Shan variety had a high content of lipid in seeds (18.45-20.09%), but the recovery rate of seeds was low (about 52.77%). In contrast, the Trungdu variety had a high seed recovery rate (about 64.6%), and the lipid content in the seed was also good (18-20%). Oil quality was determined by physical and chemical indicators (peroxide value, acid value, iodine value, saponification value); Criteria for evaluation of antioxidant capacity (total polyphenols, DPPH free radical scavenging ability through IC50, total carotenoids) of all 15 samples and fatty acid composition in some samples were evaluated as raw materials for producing tea seed oils. In term of oil quality, the tea varieties did not significantly affect the chemical quality and fatty acid composition of tea seed oils. However, DPPH free radical scavenging ability and carotenoid content were the best in Shan seed oil samples in all cultivation places and Trung Du seed oil samples in Phu Tho. Fatty acid profiles of 3 oil samples (2 samples of Trung du seed oil in Phu Tho and Tuyen Quang provinces; 1 samples of Shan seed oil in Yen Bai province) showed that tea seed oil had a high quality.

 

Vietnam’s border trade: Current situation and issues

Border economic cooperation and border trade among neighboring countries in particular, are being proved to be increasingly effective for the mutual benefits of the participants, especially for the country with a long border like Vietnam. The study exhibited that the trade between Vietnam and three neighboring countries has developed rapidly, especially the trade between Vietnam and China. However, the Government and localities should have solutions for important issues like infrastructure and for difficulties in developing the local business community as well as the policy harmonisation with the neighboring countries.